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SARS-CoV2 variant-specific replicating RNA vaccines protect from disease and pathology and reduce viral shedding following challenge with heterologous SARS-CoV2 variants of concern

Despite mass public health efforts, the SARS-CoV2 pandemic continues as of late-2021 with resurgent case numbers in many parts of the world. The emergence of SARS-CoV2 variants of concern (VoC) and evidence that existing vaccines that were designed to protect from the original strains of SARS-CoV-2...

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Detalles Bibliográficos
Autores principales: Hawman, David W., Meade-White, Kimberly, Archer, Jacob, Leventhal, Shanna, Wilson, Drew, Shaia, Carl, Randall, Samantha, Khandhar, Amit P., Hsiang, Tien-Ying, Gale, Michael, Berglund, Peter, Fuller, Deborah Heydenburg, Feldmann, Heinz, Erasmus, Jesse H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8687464/
https://www.ncbi.nlm.nih.gov/pubmed/34931189
http://dx.doi.org/10.1101/2021.12.10.472134