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Structural models of SARS-CoV-2 Omicron variant in complex with ACE2 receptor or antibodies suggest altered binding interfaces

There is enormous ongoing interest in characterizing the binding properties of the SARS-CoV-2 Omicron Variant of Concern (VOC) (B.1.1.529), which continues to spread towards potential dominance worldwide. To aid these studies, based on the wealth of available structural information about several SAR...

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Detalles Bibliográficos
Autores principales: Lubin, Joseph H., Markosian, Christopher, Balamurugan, D., Pasqualini, Renata, Arap, Wadih, Burley, Stephen K., Khare, Sagar D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8687476/
https://www.ncbi.nlm.nih.gov/pubmed/34931193
http://dx.doi.org/10.1101/2021.12.12.472313