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Cell Surface SARS-CoV-2 Nucleocapsid Protein Modulates Innate and Adaptive Immunity

SARS-CoV-2 nucleocapsid protein (N) induces strong antibody and T cell responses. Although considered to be localized in the cytosol, we readily detect N on the surface of live cells. N released by SARS-CoV-2 infected cells or N-expressing transfected cells binds to neighboring cells by electrostati...

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Detalles Bibliográficos
Autores principales: López-Muñoz, Alberto Domingo, Kosik, Ivan, Holly, Jaroslav, Yewdell, Jonathan W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8687480/
https://www.ncbi.nlm.nih.gov/pubmed/34931195
http://dx.doi.org/10.1101/2021.12.10.472169