Cargando…

Multifunctional RNA-binding proteins influence mRNA abundance and translational efficiency of distinct sets of target genes

RNA-binding proteins (RBPs) can regulate more than a single aspect of RNA metabolism. We searched for such previously undiscovered multifunctionality within a set of 143 RBPs, by defining the predictive value of RBP abundance for the transcription and translation levels of known RBP target genes acr...

Descripción completa

Detalles Bibliográficos
Autores principales: Schneider-Lunitz, Valentin, Ruiz-Orera, Jorge, Hubner, Norbert, van Heesch, Sebastiaan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8687540/
https://www.ncbi.nlm.nih.gov/pubmed/34879078
http://dx.doi.org/10.1371/journal.pcbi.1009658