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Slowdown of Water Dynamics from the Top to the Bottom of the GroEL Cavity

[Image: see text] The GroE molecular chaperone system is a critical protein machine that assists the folding of substrate proteins in its cavity. Water in the cavity is suspected to play a role in substrate protein folding, but the mechanism is currently unknown. Herein, we report measurements of wa...

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Detalles Bibliográficos
Autores principales: Macro, Nicolas, Chen, Long, Yang, Yushan, Mondal, Tridib, Wang, Lijuan, Horovitz, Amnon, Zhong, Dongping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8687601/
https://www.ncbi.nlm.nih.gov/pubmed/34129341
http://dx.doi.org/10.1021/acs.jpclett.1c01216