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Altered temporal sequence of transcriptional regulators in the generation of human cerebellar granule cells

Brain development is regulated by conserved transcriptional programs across species, but little is known about the divergent mechanisms that create species-specific characteristics. Among brain regions, human cerebellar histogenesis differs in complexity compared with nonhuman primates and rodents,...

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Detalles Bibliográficos
Autores principales: Behesti, Hourinaz, Kocabas, Arif, Buchholz, David E, Carroll, Thomas S, Hatten, Mary E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8687658/
https://www.ncbi.nlm.nih.gov/pubmed/34842137
http://dx.doi.org/10.7554/eLife.67074