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Zingiberensis Newsaponin Inhibits the Malignant Progression of Hepatocellular Carcinoma via Suppressing Autophagy Moderated by the AKR1C1-Mediated JAK2/STAT3 Pathway

OBJECTIVE: Saponins are a group of compounds from various plants, which exhibit an anticancer activity. This study aimed to explore the anticancer effect of zingiberensis newsaponin (ZnS) against hepatocellular carcinoma (HCC) and the underlying mechanism involving autophagy. METHODS: HCC cells (Huh...

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Detalles Bibliográficos
Autores principales: He, Keqing, Liu, Xing, Cheng, Shiping, Zhou, Pingsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8687772/
https://www.ncbi.nlm.nih.gov/pubmed/34938341
http://dx.doi.org/10.1155/2021/4055209