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Peroxisomal β-oxidation acts as a sensor for intracellular fatty acids and regulates lipolysis

To liberate fatty acids (FAs) from intracellular stores, lipolysis is regulated by the activity of the lipases adipose triglyceride lipase (ATGL), hormone-sensitive lipase and monoacylglycerol lipase. Excessive FA release as a result of uncontrolled lipolysis results in lipotoxicity, which can in tu...

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Detalles Bibliográficos
Autores principales: Ding, Lianggong, Sun, Wenfei, Balaz, Miroslav, He, Anyuan, Klug, Manuel, Wieland, Stefan, Caiazzo, Robert, Raverdy, Violeta, Pattou, Francois, Lefebvre, Philippe, Lodhi, Irfan J., Staels, Bart, Heim, Markus, Wolfrum, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688145/
https://www.ncbi.nlm.nih.gov/pubmed/34903883
http://dx.doi.org/10.1038/s42255-021-00489-2