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Genome editing of therapeutic T cells

The potential of engineered TCRαβ T cells as potent mediators of leukemic clearance has been demonstrated in clinical trials, and authorised therapies are being deployed against B cell malignancies in particular. While most applications have relied on harvest and manipulation of autologous lymphocyt...

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Detalles Bibliográficos
Autor principal: Qasim, Waseem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688148/
https://www.ncbi.nlm.nih.gov/pubmed/34977824
http://dx.doi.org/10.1016/j.ggedit.2021.100010