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Genome editing of therapeutic T cells
The potential of engineered TCRαβ T cells as potent mediators of leukemic clearance has been demonstrated in clinical trials, and authorised therapies are being deployed against B cell malignancies in particular. While most applications have relied on harvest and manipulation of autologous lymphocyt...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688148/ https://www.ncbi.nlm.nih.gov/pubmed/34977824 http://dx.doi.org/10.1016/j.ggedit.2021.100010 |