Transcriptome signature of cell viability predicts drug response and drug interaction in Mycobacterium tuberculosis

There is an urgent need for new drug regimens to rapidly cure tuberculosis. Here, we report the development of drug response assayer (DRonA) and “MLSynergy,” algorithms to perform rapid drug response assays and predict response of Mycobacterium tuberculosis (Mtb) to drug combinations. Using a transc...

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Detalles Bibliográficos
Autores principales: Srinivas, Vivek, Ruiz, Rene A., Pan, Min, Immanuel, Selva Rupa Christinal, Peterson, Eliza J.R., Baliga, Nitin S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688151/
https://www.ncbi.nlm.nih.gov/pubmed/34977849
http://dx.doi.org/10.1016/j.crmeth.2021.100123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688151/
https://www.ncbi.nlm.nih.gov/pubmed/34977849
http://dx.doi.org/10.1016/j.crmeth.2021.100123

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