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Distinct classes of potassium channels fused to GPCRs as electrical signaling biosensors

Ligand-gated ion channels (LGICs) are natural biosensors generating electrical signals in response to the binding of specific ligands. Creating de novo LGICs for biosensing applications is technically challenging. We have previously designed modified LGICs by linking G protein-coupled receptors (GPC...

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Detalles Bibliográficos
Autores principales: García-Fernández, M. Dolores, Chatelain, Franck C., Nury, Hugues, Moroni, Anna, Moreau, Christophe J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688152/
https://www.ncbi.nlm.nih.gov/pubmed/34977850
http://dx.doi.org/10.1016/j.crmeth.2021.100119