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Distinct classes of potassium channels fused to GPCRs as electrical signaling biosensors
Ligand-gated ion channels (LGICs) are natural biosensors generating electrical signals in response to the binding of specific ligands. Creating de novo LGICs for biosensing applications is technically challenging. We have previously designed modified LGICs by linking G protein-coupled receptors (GPC...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688152/ https://www.ncbi.nlm.nih.gov/pubmed/34977850 http://dx.doi.org/10.1016/j.crmeth.2021.100119 |