SENP2 Reduces Hepatocellular Carcinoma Stemness and Improves Sorafenib Sensitivity Through Inactivating the AKT/GSK3β/CTNNB1 Pathway

BACKGROUND: Small ubiquitin-like modifier specific peptidase 2 (SENP2) suppresses the progression and chemoresistance of several cancers, while few studies report its role in hepatocellular carcinoma (HCC). This study aimed to evaluate the effect of SENP2 on stemness, sorafenib sensitivity, and down...

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Detalles Bibliográficos
Autores principales: Tang, Xiaohui, Liu, Bohao, Zhang, Chen, Tang, Wenbin, Liang, Shitian, Xiao, Yadan, Deng, Ruoyu, Li, Zhuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688154/
https://www.ncbi.nlm.nih.gov/pubmed/34950583
http://dx.doi.org/10.3389/fonc.2021.773045

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688154/
https://www.ncbi.nlm.nih.gov/pubmed/34950583
http://dx.doi.org/10.3389/fonc.2021.773045

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