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Antibacterial Discovery via Phenotypic DNA-Encoded Library Screening

[Image: see text] The global rise of multidrug resistant infections poses an imminent, existential threat. Numerous pipelines have failed to convert biochemically active molecules into bona fide antibacterials, owing to a lack of chemical material with antibacterial-like physical properties in high-...

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Detalles Bibliográficos
Autores principales: Cochrane, Wesley G., Fitzgerald, Patrick R., Paegel, Brian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688339/
https://www.ncbi.nlm.nih.gov/pubmed/34806373
http://dx.doi.org/10.1021/acschembio.1c00714