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Primary Tumor Suppression and Systemic Immune Activation of Macrophages through the Sting Pathway in Metastatic Skin Tumor

PURPOSE: Agonists of the stimulator of interferon genes (STING) play a key role in activating the STING pathway by promoting the production of cytokines. In this study, we investigated the antitumor effects and activation of the systemic immune response of treatment with DMXAA (5,6-dimethylxanthenon...

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Detalles Bibliográficos
Autores principales: Synn, Chun-Bong, Kim, Dong Kwon, Kim, Jae Hwan, Byeon, Youngseon, Kim, Young Seob, Yun, Mi Ran, Lee, Ji Min, Lee, Wongeun, Lee, Eun Ji, Lee, Seul, Lee, You-Won, Lee, Doo Jae, Kim, Hyun-Woo, Kim, Chang Gon, Hong, Min Hee, Park, June Dong, Lim, Sun Min, Pyo, Kyoung-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Yonsei University College of Medicine 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688365/
https://www.ncbi.nlm.nih.gov/pubmed/34913283
http://dx.doi.org/10.3349/ymj.2022.63.1.42