ABT-737, a BH3 Mimetic, Enhances the Therapeutic Effects of Ionizing Radiation in K-ras Mutant Non-Small Cell Lung Cancer Preclinical Model

PURPOSE: Tumor radioresistance and dose-limiting toxicity restrict the curative potential of radiotherapy, requiring novel approaches to overcome the limitations and augment the efficacy. Here, we investigated the effects of signal transducer and activator of transcription 3 (STAT3) activation and a...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Jung Mo, Kim, Hey Soo, Kim, Arum, Chang, Yoon Soo, Lee, Jin Gu, Cho, Jaeho, Kim, Eun Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Yonsei University College of Medicine 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688371/
https://www.ncbi.nlm.nih.gov/pubmed/34913280
http://dx.doi.org/10.3349/ymj.2022.63.1.16

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688371/
https://www.ncbi.nlm.nih.gov/pubmed/34913280
http://dx.doi.org/10.3349/ymj.2022.63.1.16

Ejemplares similares