Catalpol Inhibits Tregs-to-Th17 Cell Transdifferentiation by Up-Regulating Let-7g-5p to Reduce STAT3 Protein Levels

PURPOSE: Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease, and Th17 cells are key factors in the pathogenesis of human inflammatory conditions, such as RA. Catalpol (CAT), a component in Rehmanniae Radix (RR), has been found to regulate human immunity. However, the effects of CAT o...

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Detalles Bibliográficos
Autores principales: Di, Yuxi, Zhang, Mingfei, Chen, Yichang, Sun, Ruonan, Shen, Meiyu, Tian, Fengxiang, Yang, Pei, Qian, Feiya, Zhou, Lingling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Yonsei University College of Medicine 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688372/
https://www.ncbi.nlm.nih.gov/pubmed/34913284
http://dx.doi.org/10.3349/ymj.2022.63.1.56

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688372/
https://www.ncbi.nlm.nih.gov/pubmed/34913284
http://dx.doi.org/10.3349/ymj.2022.63.1.56

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