Inflammatory activation of surface molecule shedding by upregulation of the pseudoprotease iRhom2 in colon epithelial cells

The metalloproteinase ADAM17 contributes to inflammatory and proliferative responses by shedding of cell-surface molecules. By this ADAM17 is implicated in inflammation, regeneration, and permeability regulation of epithelial cells in the colon. ADAM17 maturation and surface expression requires the...

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Detalles Bibliográficos
Autores principales: Giese, Anja Adelina, Babendreyer, Aaron, Krappen, Peter, Gross, Annika, Strnad, Pavel, Düsterhöft, Stefan, Ludwig, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688420/
https://www.ncbi.nlm.nih.gov/pubmed/34930929
http://dx.doi.org/10.1038/s41598-021-03522-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688420/
https://www.ncbi.nlm.nih.gov/pubmed/34930929
http://dx.doi.org/10.1038/s41598-021-03522-2

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