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Three topological features of regulatory networks control life-essential and specialized subsystems

Gene regulatory networks (GRNs) play key roles in development, phenotype plasticity, and evolution. Although graph theory has been used to explore GRNs, associations amongst topological features, transcription factors (TFs), and systems essentiality are poorly understood. Here we sought the relation...

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Detalles Bibliográficos
Autores principales: Wolf, Ivan Rodrigo, Simões, Rafael Plana, Valente, Guilherme Targino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688434/
https://www.ncbi.nlm.nih.gov/pubmed/34930908
http://dx.doi.org/10.1038/s41598-021-03625-w