Contributions of Na(V)1.8 and Na(V)1.9 to excitability in human induced pluripotent stem-cell derived somatosensory neurons

The inhibition of voltage-gated sodium (Na(V)) channels in somatosensory neurons presents a promising novel modality for the treatment of pain. However, the precise contribution of these channels to neuronal excitability, the cellular correlate of pain, is unknown; previous studies using genetic kno...

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Detalles Bibliográficos
Autores principales: Alsaloum, Matthew, Labau, Julie I. R., Liu, Shujun, Estacion, Mark, Zhao, Peng, Dib-Hajj, Fadia, Waxman, Stephen G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688473/
https://www.ncbi.nlm.nih.gov/pubmed/34930944
http://dx.doi.org/10.1038/s41598-021-03608-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688473/
https://www.ncbi.nlm.nih.gov/pubmed/34930944
http://dx.doi.org/10.1038/s41598-021-03608-x

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