Differential brain ADRA2A and ADRA2C gene expression and epigenetic regulation in schizophrenia. Effect of antipsychotic drug treatment

Postsynaptic α(2A)-adrenoceptor density is enhanced in the dorsolateral prefrontal cortex (DLPFC) of antipsychotic-treated schizophrenia subjects. This alteration might be due to transcriptional activation, and could be regulated by epigenetic mechanisms such as histone posttranslational modificatio...

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Detalles Bibliográficos
Autores principales: Brocos-Mosquera, Iria, Miranda-Azpiazu, Patricia, Muguruza, Carolina, Corzo-Monje, Virginia, Morentin, Benito, Meana, J. Javier, Callado, Luis F., Rivero, Guadalupe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688495/
https://www.ncbi.nlm.nih.gov/pubmed/34930904
http://dx.doi.org/10.1038/s41398-021-01762-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688495/
https://www.ncbi.nlm.nih.gov/pubmed/34930904
http://dx.doi.org/10.1038/s41398-021-01762-4

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