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Differential brain ADRA2A and ADRA2C gene expression and epigenetic regulation in schizophrenia. Effect of antipsychotic drug treatment
Postsynaptic α(2A)-adrenoceptor density is enhanced in the dorsolateral prefrontal cortex (DLPFC) of antipsychotic-treated schizophrenia subjects. This alteration might be due to transcriptional activation, and could be regulated by epigenetic mechanisms such as histone posttranslational modificatio...
Autores principales: | Brocos-Mosquera, Iria, Miranda-Azpiazu, Patricia, Muguruza, Carolina, Corzo-Monje, Virginia, Morentin, Benito, Meana, J. Javier, Callado, Luis F., Rivero, Guadalupe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688495/ https://www.ncbi.nlm.nih.gov/pubmed/34930904 http://dx.doi.org/10.1038/s41398-021-01762-4 |
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