Pneumococcal capsule blocks protection by immunization with conserved surface proteins

Vaccines targeting Streptococcus pneumoniae (Spn) are limited by dependence on capsular polysaccharide and its serotype diversity. More broadly-based approaches using common protein antigens have not resulted in a licensed vaccine. Herein, we used an unbiased, genome-wide approach to find novel vacc...

Descripción completa

Detalles Bibliográficos
Autores principales: Zangari, Tonia, Zafar, M. Ammar, Lees, John A., Abruzzo, Annie R., Bee, Gavyn Chern Wei, Weiser, Jeffrey N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688510/
https://www.ncbi.nlm.nih.gov/pubmed/34930916
http://dx.doi.org/10.1038/s41541-021-00413-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688510/
https://www.ncbi.nlm.nih.gov/pubmed/34930916
http://dx.doi.org/10.1038/s41541-021-00413-5

Ejemplares similares