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Pneumococcal capsule blocks protection by immunization with conserved surface proteins

Vaccines targeting Streptococcus pneumoniae (Spn) are limited by dependence on capsular polysaccharide and its serotype diversity. More broadly-based approaches using common protein antigens have not resulted in a licensed vaccine. Herein, we used an unbiased, genome-wide approach to find novel vacc...

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Detalles Bibliográficos
Autores principales:	Zangari, Tonia, Zafar, M. Ammar, Lees, John A., Abruzzo, Annie R., Bee, Gavyn Chern Wei, Weiser, Jeffrey N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688510/ https://www.ncbi.nlm.nih.gov/pubmed/34930916 http://dx.doi.org/10.1038/s41541-021-00413-5

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