WTIP upregulates FOXO3a and induces apoptosis through PUMA in acute myeloid leukemia

Acute myeloid leukemia (AML) is an aggressive and heterogeneous clonal hematologic malignancy for which novel therapeutic targets and strategies are required. Emerging evidence suggests that WTIP is a candidate tumor suppressor. However, the molecular mechanisms of WTIP in leukemogenesis have not be...

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Detalles Bibliográficos
Autores principales: Zhu, Yunqi, Tong, Xiangmin, Wang, Ying, Lu, Xiaoya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688515/
https://www.ncbi.nlm.nih.gov/pubmed/34930905
http://dx.doi.org/10.1038/s41419-021-04467-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688515/
https://www.ncbi.nlm.nih.gov/pubmed/34930905
http://dx.doi.org/10.1038/s41419-021-04467-0

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