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Reversible insulin resistance in muscle and fat unrelated to the metabolic syndrome in patients with acromegaly

BACKGROUND: Patients with active acromegaly exhibit insulin resistance despite a lean phenotype whereas controlled disease improves insulin sensitivity and increases fat mass. The mechanisms underlying this paradox remain elusive, but growth hormone (GH)-induced lipolysis plays a central role. The a...

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Detalles Bibliográficos
Autores principales: Arlien-Søborg, Mai C., Dal, Jakob, Madsen, Michael Alle, Høgild, Morten Lyng, Hjelholt, Astrid Johannesson, Pedersen, Steen B., Møller, Niels, Jessen, Niels, Jørgensen, Jens O.L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688588/
https://www.ncbi.nlm.nih.gov/pubmed/34929488
http://dx.doi.org/10.1016/j.ebiom.2021.103763