Dysregulation of Notch-FGF signaling axis in germ cells results in cystic dilation of the rete testis in mice

Numb (Nb) and Numb-like (Nbl) are functionally redundant adaptor proteins that critically regulate cell fate and morphogenesis in a variety of organs. We selectively deleted Nb and Nbl in testicular germ cells by breeding Nb/Nbl floxed mice with a transgenic mouse line Tex101-Cre. The mutant mice de...

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Detalles Bibliográficos
Autores principales: Cao, Yin, Liu, Lingyun, Lin, Jing, Sun, Penghao, Guo, Kaimin, Li, Shengqiang, Li, Xian, Lan, Zi-jian, Wang, Hongliang, Lei, Zhenmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688682/
https://www.ncbi.nlm.nih.gov/pubmed/34101112
http://dx.doi.org/10.1007/s12079-021-00628-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688682/
https://www.ncbi.nlm.nih.gov/pubmed/34101112
http://dx.doi.org/10.1007/s12079-021-00628-0

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