Lipidomic Analyses Uncover Apoptotic and Inhibitory Effects of Pyrvinium Pamoate on Cholangiocarcinoma Cells via Mitochondrial Membrane Potential Dysfunction

Pyrvinium pamoate (PP), an FDA-approved anthelmintic drug, has been validated as a highly potent anti-cancer agent and patented recently as a potential chemotherapeutic drug for various cancers. The aims of this study were, therefore, to investigate the ability of PP in anti-proliferative activity a...

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Detalles Bibliográficos
Autores principales: Kittirat, Yingpinyapat, Phetcharaburanin, Jutarop, Promraksa, Bundit, Kulthawatsiri, Thanaporn, Wangwiwatsin, Arporn, Klanrit, Poramate, Sangkhamanon, Sakkarn, Jarearnrat, Apiwat, Thongchot, Suyanee, Mahalapbutr, Panupong, Loilome, Watcharin, Saya, Hideyuki, Namwat, Nisana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Public Health
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688698/
https://www.ncbi.nlm.nih.gov/pubmed/34950627
http://dx.doi.org/10.3389/fpubh.2021.766455

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688698/
https://www.ncbi.nlm.nih.gov/pubmed/34950627
http://dx.doi.org/10.3389/fpubh.2021.766455

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