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The role of genetic modifiers, inflammation and CFTR in the pathogenesis of Cystic fibrosis related diabetes
Cystic fibrosis related diabetes (CFRD) generally reflects insufficient and/or delayed production of insulin, developing slowly over years to decades. Multiple mechanisms have been implicated in the pathogenesis of CFRD. CFTR function itself is a strong determinant of CFRD risk. Variants in CFTR tha...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688704/ https://www.ncbi.nlm.nih.gov/pubmed/34976741 http://dx.doi.org/10.1016/j.jcte.2021.100287 |