The role of genetic modifiers, inflammation and CFTR in the pathogenesis of Cystic fibrosis related diabetes

Cystic fibrosis related diabetes (CFRD) generally reflects insufficient and/or delayed production of insulin, developing slowly over years to decades. Multiple mechanisms have been implicated in the pathogenesis of CFRD. CFTR function itself is a strong determinant of CFRD risk. Variants in CFTR tha...

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Detalles Bibliográficos
Autores principales: Hasan, Sana, Soltman, Sarah, Wood, Colleen, Blackman, Scott M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Special Issue: CF Endocrinology Advance
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688704/
https://www.ncbi.nlm.nih.gov/pubmed/34976741
http://dx.doi.org/10.1016/j.jcte.2021.100287

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