Direct Inhibition of Microglia Activation by Pretreatment With Botulinum Neurotoxin A for the Prevention of Neuropathic Pain

Peripheral injection of botulinum neurotoxin A (BoNT/A) has been demonstrated to have a long-term analgesic effect in treating neuropathic pain. Around peripheral nerves, BoNT/A is taken up by primary afferent neurons and inhibits neuropeptide release. Moreover, BoNT/A could also be retrogradely tra...

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Detalles Bibliográficos
Autores principales: Feng, Xiaona, Xiong, Donglin, Li, Jie, Xiao, Lizu, Xie, Weijiao, Qiu, Yunhai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688716/
https://www.ncbi.nlm.nih.gov/pubmed/34949981
http://dx.doi.org/10.3389/fnins.2021.760403

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688716/
https://www.ncbi.nlm.nih.gov/pubmed/34949981
http://dx.doi.org/10.3389/fnins.2021.760403

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