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A Novel Humanized Model of NASH and Its Treatment With META4, A Potent Agonist of MET

BACKGROUND & AIMS: Nonalcoholic fatty liver disease is a frequent cause of hepatic dysfunction and is now a global epidemic. This ailment can progress to an advanced form called nonalcoholic steatohepatitis (NASH) and end-stage liver disease. Currently, the molecular basis of NASH pathogenesis i...

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Detalles Bibliográficos
Autores principales: Ma, Jihong, Tan, Xinping, Kwon, Yongkook, Delgado, Evan R., Zarnegar, Arman, DeFrances, Marie C., Duncan, Andrew W., Zarnegar, Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688725/
https://www.ncbi.nlm.nih.gov/pubmed/34756982
http://dx.doi.org/10.1016/j.jcmgh.2021.10.007