Drug Repurposing: Deferasirox Inhibits the Anti-Apoptotic Activity of Mcl-1

INTRODUCTION: With the aim of repositioning commercially available drugs for the inhibition of the anti-apoptotic myeloid cell leukemia protein, Mcl-1, implied in various cancers, five molecules, highlighted from a published theoretical screening, were selected to experimentally validate their affin...

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Detalles Bibliográficos
Autores principales: Bourafai-Aziez, Asma, Benabderrahmane, Mohammed, Paysant, Hippolyte, Weiswald, Louis-Bastien, Poulain, Laurent, Carlier, Ludovic, Ravault, Delphine, Jouanne, Marie, Coadou, Gaël, Oulyadi, Hassan, Voisin-Chiret, Anne-Sophie, Sopková-de Oliveira Santos, Jana, Sebban, Muriel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688747/
https://www.ncbi.nlm.nih.gov/pubmed/34949914
http://dx.doi.org/10.2147/DDDT.S323077

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688747/
https://www.ncbi.nlm.nih.gov/pubmed/34949914
http://dx.doi.org/10.2147/DDDT.S323077

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