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Multiple Tolerization Subtractive Immunization (MTSI) Protocol: Effects on Mice and Monoclonal Antibody Specificity

Monoclonal antibodies (mAbs) have been a valuable tool to elucidate several biological processes, such as stem cell differentiation and cancer, and contributed to virtually all areas of biomedical sciences. Yet, it remains a challenge to obtain mAbs specific to poorly expressed epitopes, or to epito...

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Detalles Bibliográficos
Autores principales: de Lima Fontes, Marina, Neves, Franciny Mara de Lima, Santos, Kelvin Sousa, Fusco-Almeida, Ana Marisa, Giannini, Maria José Soares Mendes, Felisbino, Sergio Luis, Deffune, Elenice, Moroz, Andrei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688850/
https://www.ncbi.nlm.nih.gov/pubmed/34950138
http://dx.doi.org/10.3389/fimmu.2021.760817