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Citrullinated Histone H3 Mediates Sepsis-Induced Lung Injury Through Activating Caspase-1 Dependent Inflammasome Pathway

Sepsis is a life-threatening organ dysfunction caused by dysregulated host response to infection that often results in acute lung injury (ALI)/acute respiratory distress syndrome (ARDS). An emerging mechanism of sepsis-induced ARDS involves neutrophils/macrophages undergoing cell death, releasing nu...

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Detalles Bibliográficos
Autores principales: Tian, Yuzi, Li, Patrick, Wu, Zhenyu, Deng, Qiufang, Pan, Baihong, Stringer, Kathleen A., Alam, Hasan B., Standiford, Theodore J., Li, Yongqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688857/
https://www.ncbi.nlm.nih.gov/pubmed/34950139
http://dx.doi.org/10.3389/fimmu.2021.761345