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Screening for Activity Against AMPA Receptors Among Anticonvulsants—Focus on Phenytoin

The interest in AMPA receptors as a target for epilepsy treatment increased substantially after the approval of perampanel, a negative AMPA receptor allosteric antagonist, for the treatment of partial-onset seizures and generalized tonic-clonic seizures. Here we performed a screening for activity ag...

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Detalles Bibliográficos
Autores principales: Dron, M. Y., Zhigulin, A. S., Tikhonov, D. B., Barygin, O. I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688955/
https://www.ncbi.nlm.nih.gov/pubmed/34950035
http://dx.doi.org/10.3389/fphar.2021.775040