Protumorigenic Role of Elevated Levels of DNA Polymerase Epsilon Predicts an Immune-Suppressive Microenvironment in Clear Cell Renal Cell Carcinoma

Increasing evidence indicates that DNA polymerase epsilon (POLE), which mediates DNA damage repair, is significantly associated with tumor prognosis. This study aimed to analyze POLE expression in tumor samples and its prognostic value for patients with clear cell renal cell carcinoma (ccRCC). We fo...

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Detalles Bibliográficos
Autores principales: Wu, Xiaohui, Tang, Haijia, Xu, Wen-Hao, Tang, Haidan, Wei, Shiyin, Anwaier, Aihetaimujiang, Huang, Haineng, Qu, Yuan-Yuan, Zhang, Hailiang, Zhao, Shuai, Li, Hui, Liu, Wangrui, Chen, Hongjing, Ding, Chen, Ye, Dingwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8689073/
https://www.ncbi.nlm.nih.gov/pubmed/34950188
http://dx.doi.org/10.3389/fgene.2021.751977

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8689073/
https://www.ncbi.nlm.nih.gov/pubmed/34950188
http://dx.doi.org/10.3389/fgene.2021.751977

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