N6-Methyladenosine Methyltransferase METTL3 Promotes Angiogenesis and Atherosclerosis by Upregulating the JAK2/STAT3 Pathway via m6A Reader IGF2BP1

Atherosclerosis (AS) is a life-threatening vascular disease. RNA N6-methyladenosine (m6A) modification level is dysregulated in multiple pathophysiologic processes including AS. In this text, the roles and molecular mechanisms of m6A writer METTL3 in AS progression were explored in vitro and in vivo...

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Detalles Bibliográficos
Autores principales: Dong, Guo, Yu, Jiangbo, Shan, Gaojun, Su, Lide, Yu, Nannan, Yang, Shusen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8689138/
https://www.ncbi.nlm.nih.gov/pubmed/34950654
http://dx.doi.org/10.3389/fcell.2021.731810

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8689138/
https://www.ncbi.nlm.nih.gov/pubmed/34950654
http://dx.doi.org/10.3389/fcell.2021.731810

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