Discovery of a Positive Allosteric Modulator of Cholecystokinin Action at CCK1R in Normal and Elevated Cholesterol

Drugs useful in prevention/treatment of obesity could improve health. Cholecystokinin (CCK) is a key regulator of appetite, working through the type 1 CCK receptor (CCK1R); however, full agonists have not stimulated more weight loss than dieting. We proposed an alternate strategy to target this rece...

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Detalles Bibliográficos
Autores principales: Harikumar, Kaleeckal G., Coudrat, Thomas, Desai, Aditya J., Dong, Maoqing, Dengler, Daniela G., Furness, Sebastian G. B., Christopoulos, Arthur, Wootten, Denise, Sergienko, Eduard A., Sexton, Patrick M., Miller, Laurence J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8689142/
https://www.ncbi.nlm.nih.gov/pubmed/34950108
http://dx.doi.org/10.3389/fendo.2021.789957

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8689142/
https://www.ncbi.nlm.nih.gov/pubmed/34950108
http://dx.doi.org/10.3389/fendo.2021.789957

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