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Impact of benzalkonium chloride-preserved and preservative-free latanoprost eye drops on cultured human conjunctival goblet cells upon acute exposure and differences in physicochemical properties of the eye drops

OBJECTIVE: To investigate the short-term impact on human conjunctival goblet cell (GC) survival and mucin release of acute exposure to benzalkonium chloride (BAK) preserved and preservative-free (PF) 0.005% (w/v) latanoprost (LT) eye drops, and to compare the eye drops’ physicochemical properties. M...

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Detalles Bibliográficos
Autores principales: Müllertz, Olivia, Hedengran, Anne, Mouhammad, Zaynab Ahmad, Freiberg, Josefine, Nagymihály, Richárd, Jacobsen, Jette, Larsen, Susan Weng, Bair, Jeffrey, Utheim, Tor P, Dartt, Darlene A, Heegaard, Steffen, Petrovski, Goran, Kolko, Miriam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8689192/
https://www.ncbi.nlm.nih.gov/pubmed/34993350
http://dx.doi.org/10.1136/bmjophth-2021-000892