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A new insect cell line engineered to produce recombinant glycoproteins with cleavable N-glycans

Glycoproteins are difficult to crystallize because they have heterogeneous glycans composed of multiple monosaccharides with considerable rotational freedom about their O-glycosidic linkages. Crystallographers studying N-glycoproteins often circumvent this problem by using β1,2-N-acetylglucosaminylt...

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Detalles Bibliográficos
Autores principales: Mabashi-Asazuma, Hideaki, Jarvis, Donald L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8689212/
https://www.ncbi.nlm.nih.gov/pubmed/34838817
http://dx.doi.org/10.1016/j.jbc.2021.101454