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The G4 resolvase RHAU regulates ventricular trabeculation and compaction through transcriptional and post-transcriptional mechanisms

The G-quadruplex (G4) resolvase RNA helicase associated with AU-rich element (RHAU) possesses the ability to unwind G4 structures in both DNA and RNA molecules. Previously, we revealed that RHAU plays a critical role in embryonic heart development and postnatal heart function through modulating mRNA...

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Detalles Bibliográficos
Autores principales: Huang, Xinyi, Zhao, Ke, Jiang, Mingyang, Qiu, Dehui, Zhou, Jun, Yang, Zhongzhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8689214/
https://www.ncbi.nlm.nih.gov/pubmed/34838591
http://dx.doi.org/10.1016/j.jbc.2021.101449