Cargando…

The G4 resolvase RHAU regulates ventricular trabeculation and compaction through transcriptional and post-transcriptional mechanisms

The G-quadruplex (G4) resolvase RNA helicase associated with AU-rich element (RHAU) possesses the ability to unwind G4 structures in both DNA and RNA molecules. Previously, we revealed that RHAU plays a critical role in embryonic heart development and postnatal heart function through modulating mRNA...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huang, Xinyi, Zhao, Ke, Jiang, Mingyang, Qiu, Dehui, Zhou, Jun, Yang, Zhongzhou
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8689214/ https://www.ncbi.nlm.nih.gov/pubmed/34838591 http://dx.doi.org/10.1016/j.jbc.2021.101449

Ejemplares similares

The G4 resolvase RHAU modulates mRNA translation and stability to sustain postnatal heart function and regeneration
por: Jiang, Mingyang, et al.
Publicado: (2020)

To unwind the biological knots: The DNA/RNA G‐quadruplex resolvase RHAU (DHX36) in development and disease
por: Yang, Chensi, et al.
Publicado: (2022)

A G-quadruplex DNA structure resolvase, RHAU, is essential for spermatogonia differentiation
por: Gao, X, et al.
Publicado: (2015)

Impact of Right Ventricular Trabeculation on Right Ventricular Function in Patients With Left Ventricular Non-compaction Phenotype
por: Kiss, Anna Réka, et al.
Publicado: (2022)

The RNA helicase RHAU (DHX36) suppresses expression of the transcription factor PITX1
por: Booy, Evan P., et al.
Publicado: (2014)

Trabeculated (non-compacted) and compact myocardium in adults: the multi-ethnic study of atherosclerosis
por: Kawel, Nadine, et al.
Publicado: (2012)

Assessment of right and left ventricular trabeculation in a reference collective: gender and age dependency of myocardial trabeculation
por: Burger, Astrid, et al.
Publicado: (2011)

Assessment of left and right ventricular trabeculation and non-compacted myocardium in a large selected healthy reference population
por: Andre, Florian, et al.
Publicado: (2014)

Role of the amino terminal RHAU-specific motif in the recognition and resolution of guanine quadruplex-RNA by the DEAH-box RNA helicase RHAU
por: Lattmann, Simon, et al.
Publicado: (2010)

Left Ventricular Trabeculations in Athletes: Epiphenomenon or Phenotype of Disease?
por: Abela, Mark, et al.
Publicado: (2018)

Regional thickness of the compacted and trabeculated layers of the left ventricle in young patients presenting with ventricular dysrhythmias, a Cardiac MRI study
por: Shah, Moneal, et al.
Publicado: (2012)

Evaluation of trabeculated mass in patient with non compaction: do we need criteria reappraisal?
por: Frandon, Julien, et al.
Publicado: (2016)

Higher spatial resolution improves the interpretation of the extent of ventricular trabeculation
por: Riekerk, Hanne C. E., et al.
Publicado: (2021)

MRI morphological and functional method for clear distinction of patients with left ventricular non-compaction, inflammatory dilated cardiomyopathy and physiological myocardial trabeculation
por: Burger, Astrid, et al.
Publicado: (2012)

Assessment of the trabeculated to compacted layer ratio of the left ventricle using short and longitudinal axis views in young patients presenting with ventricular dysrhythmias
por: Shah, Moneal, et al.
Publicado: (2013)

Mechanism of recognition of parallel G-quadruplexes by DEAH/RHAU helicase DHX36 explored by molecular dynamics simulations
por: Hossain, Kazi Amirul, et al.
Publicado: (2021)

Biophysical Characterization of G-Quadruplex Recognition in the PITX1 mRNA by the Specificity Domain of the Helicase RHAU
por: Ariyo, Emmanuel O., et al.
Publicado: (2015)

RHAU helicase stabilizes G4 in its nucleotide-free state and destabilizes G4 upon ATP hydrolysis
por: You, Huijuan, et al.
Publicado: (2017)

G4 Resolvase 1 tightly binds and unwinds unimolecular G4-DNA
por: Giri, Banabihari, et al.
Publicado: (2011)

The DEAH-box RNA helicase RHAU binds an intramolecular RNA G-quadruplex in TERC and associates with telomerase holoenzyme
por: Lattmann, Simon, et al.
Publicado: (2011)

Fluid mechanics of the zebrafish embryonic heart trabeculation
por: Cairelli, Adriana Gaia, et al.
Publicado: (2022)

The catalytic residues of Tn3 resolvase
por: Olorunniji, Femi J., et al.
Publicado: (2009)

Vortex Dynamics in Trabeculated Embryonic Ventricles
por: Battista, Nicholas A., et al.
Publicado: (2019)

Impact of left ventricular trabeculations and papillary muscles on measures of cavity volume and ejection fraction
por: Chuang, Michael L, et al.
Publicado: (2011)

Fractal analysis of left ventricular trabeculations is associated with impaired myocardial deformation in healthy Chinese
por: Cai, Jiashen, et al.
Publicado: (2017)

Physical activity and left ventricular trabeculation in the UK Biobank community-based cohort study
por: Woodbridge, Simon P, et al.
Publicado: (2019)

IgG-Containing Isoforms of Neuregulin-1 Are Dispensable for Cardiac Trabeculation in Zebrafish
por: Samsa, Leigh Ann, et al.
Publicado: (2016)

Left Ventricular Trabeculations Decrease the Wall Shear Stress and Increase the Intra-Ventricular Pressure Drop in CFD Simulations
por: Sacco, Federica, et al.
Publicado: (2018)

Trabeculated Myocardium in Hypertrophic Cardiomyopathy: Clinical Consequences
por: Casanova, José David, et al.
Publicado: (2020)

A comparison of right ventricular volumes in children and adults with repaired tetralogy of Fallot - including and excluding right ventricular trabeculations
por: Enos, James D, et al.
Publicado: (2016)

Synapsis and catalysis by activated Tn3 resolvase mutants
por: Olorunniji, Femi J., et al.
Publicado: (2008)

Bulged DNA substrates for identifying poxvirus resolvase inhibitors
por: Culyba, Matthew, et al.
Publicado: (2012)

Structural basis for topological regulation of Tn3 resolvase
por: Montaño, Sherwin P, et al.
Publicado: (2022)

Semi-automatic detection of myocardial trabeculation using cardiovascular magnetic resonance: correlation with histology and reproducibility in a mouse model of non-compaction
por: Frandon, Julien, et al.
Publicado: (2018)

Cardiac Papillary Fibroelastoma in Left Ventricular Trabeculation as a Potential Cause of Cerebral Infarction: A Case Report
Publicado: (2021)

Coexistence of congenital left ventricular aneurysm and prominent left ventricular trabeculation in a patient with LDB3 mutation: a case report
por: Shan, Shengshuai, et al.
Publicado: (2017)

Structural insights into the promiscuous DNA binding and broad substrate selectivity of fowlpox virus resolvase
por: Li, Na, et al.
Publicado: (2020)

Towards an Enhanced Tool for Quantifying the Degree of LV Hyper-Trabeculation
por: Bernabé, Gregorio, et al.
Publicado: (2021)

Endocardial-Myocardial Interactions During Early Cardiac Differentiation and Trabeculation
por: Qu, Xianghu, et al.
Publicado: (2022)

Association of bladder trabeculation and neurogenic bladder with spinal cord injury
por: Won, Yu Hui, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_ddqovrel4tsuibg37om95spvpn