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Harnessing galactose oxidase in the development of a chemoenzymatic platform for glycoconjugate vaccine design

In the preparation of commercial conjugate vaccines, capsular polysaccharides (CPSs) must undergo chemical modification to generate the reactive groups necessary for covalent attachment to a protein carrier. One of the most common approaches employed for this derivatization is sodium periodate (NaIO...

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Detalles Bibliográficos
Autores principales: Duke, Jeremy A., Paschall, Amy V., Glushka, John, Lees, Andrew, Moremen, Kelley W., Avci, Fikri Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8689215/
https://www.ncbi.nlm.nih.gov/pubmed/34838818
http://dx.doi.org/10.1016/j.jbc.2021.101453