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Harnessing galactose oxidase in the development of a chemoenzymatic platform for glycoconjugate vaccine design
In the preparation of commercial conjugate vaccines, capsular polysaccharides (CPSs) must undergo chemical modification to generate the reactive groups necessary for covalent attachment to a protein carrier. One of the most common approaches employed for this derivatization is sodium periodate (NaIO...
Autores principales: | Duke, Jeremy A., Paschall, Amy V., Glushka, John, Lees, Andrew, Moremen, Kelley W., Avci, Fikri Y. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8689215/ https://www.ncbi.nlm.nih.gov/pubmed/34838818 http://dx.doi.org/10.1016/j.jbc.2021.101453 |
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