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Palmitoylated small GTPase ARL15 is translocated within Golgi network during adipogenesis

The small GTPase ARF family member ARL15 gene locus is associated in population studies with increased risk of type 2 diabetes, lower adiponectin and higher fasting insulin levels. Previously, loss of ARL15 was shown to reduce insulin secretion in a human β-cell line and loss-of-function mutations a...

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Detalles Bibliográficos
Autores principales: Wu, Yixing, Bai, Ying, McEwan, David G., Bentley, Liz, Aravani, Dimitra, Cox, Roger D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8689486/
https://www.ncbi.nlm.nih.gov/pubmed/34779483
http://dx.doi.org/10.1242/bio.058420