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High-Throughput CRISPR Screens To Dissect Macrophage-Shigella Interactions
Shigellosis causes most diarrheal deaths worldwide, particularly affecting children. Shigella invades and replicates in the epithelium of the large intestine, eliciting inflammation and tissue destruction. To understand how Shigella rewires macrophages prior to epithelium invasion, we performed geno...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Microbiology
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8689513/ https://www.ncbi.nlm.nih.gov/pubmed/34933448 http://dx.doi.org/10.1128/mBio.02158-21 |