GRWD1-WDR5-MLL2 Epigenetic Complex Mediates H3K4me3 Mark and Is Essential for Kaposi’s Sarcoma-Associated Herpesvirus-Induced Cellular Transformation

Infection by Kaposi’s sarcoma-associated herpesvirus (KSHV) is causally associated with numerous cancers. The mechanism of KSHV-induced oncogenesis remains unclear. By performing a CRISPR-Cas9 screening in a model of KSHV-induced cellular transformation of primary cells, we identified epigenetic reg...

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Detalles Bibliográficos
Autores principales: Wei, Shan, Lu, Songjian, Liang, Lifan, Wang, Xian, Li, Wan, Li, Tingting, Chen, Luping, Ju, Enguo, Zhang, Xinquan, Lai, Zhao, Huang, Yufei, Lu, Xinghua, Gao, Shou-Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8689518/
https://www.ncbi.nlm.nih.gov/pubmed/34933446
http://dx.doi.org/10.1128/mbio.03431-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8689518/
https://www.ncbi.nlm.nih.gov/pubmed/34933446
http://dx.doi.org/10.1128/mbio.03431-21

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