A J Domain Protein Functions as a Histone Chaperone to Maintain Genome Integrity and the Response to DNA Damage in a Human Fungal Pathogen

Histone chaperoning ensures genomic integrity during routine processes such as DNA replication and transcription as well as DNA repair upon damage. Here, we identify a nuclear J domain protein, Dnj4, in the fungal pathogen Cryptococcus neoformans and demonstrate that it interacts with histones 3 and...

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Detalles Bibliográficos
Autores principales: Horianopoulos, Linda C., Lee, Christopher W. J., Schmitt, Kerstin, Valerius, Oliver, Hu, Guanggan, Caza, Mélissa, Braus, Gerhard H., Kronstad, James W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8689522/
https://www.ncbi.nlm.nih.gov/pubmed/34933457
http://dx.doi.org/10.1128/mbio.03273-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8689522/
https://www.ncbi.nlm.nih.gov/pubmed/34933457
http://dx.doi.org/10.1128/mbio.03273-21

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